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One other Alzheimer’s drug fails as Lilly, AstraZeneca halt assessments

Eli Lilly and AstraZeneca ended two late-stage trials of an experimental drug for Alzheimer’s illness after the therapy failed to indicate any indicators of working, including to a litany of disappointments for the memory-robbing sickness.

An unbiased data-monitoring committee discovered that the medication, lanabecestat, was unlikely to fulfill the objectives of the research, one for early Alzheimer’s and the opposite for delicate dementia associated to the illness, the businesses stated Tuesday. There have been no security considerations, they stated.

Like a number of others that failed, reminiscent of Merck’s verubecestat, the drug focused a protein known as amyloid, regarded as a reason for the illness.

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